William Otto of Isenburg-Birstein (German: Wilhelm Otto von Isenburg-Birstein) was the Count of Isenburg-Birstein from 1628 until 1635.

Preceded by:

William Otto

Succeeded by:

Wolfgang Ernest I of Isenburg-Büdingen-Birstein Count of Isenburg-Birstein
1628 - 1635
Christian Maurice and Wolfgang Ernest II

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